r/Showerthoughts • u/MrFlow • 4h ago
Casual Thought With Ozempic/GLP-1 now being available in pill-form, all those "Take this diet pill and you will lose weight!" advertising scams in magazines back in the day are now not scams anymore.
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u/JJOne101 3h ago
Some of those were also not scams. They had tapeworm eggs in them, so you got tapeworms and lost weight.
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u/liljellybeanxo 3h ago
Don’t forget about good ol ephedrine
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u/jmartin21 3h ago
Or amphetamines! Easy to lose weight when you’re to twacked out to wanna eat
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u/SharkFart86 2h ago
Amphetamines and even methamphetamine is still occasionally prescribed for weight loss. Phentermine is commonly prescribed too, and while it’s not an amphetamine, it is an analog.
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u/jensilver95 2h ago
My provider put me on phentermine when I was first trying to lose weight with medicine and that was a mistake, had me so wired I had to stop after a week when my parents pointed out I sounded crazier than usual. I have anxiety already so I'm not sure the phentermine was a great idea in the first place.
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u/ItsMeVeriity 2h ago
Phenterage the thing they also don't talk about and discredit as a thing. :) some of the kindest people turn into Hulk over the smallest slights
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u/Sweatybutthole 2h ago edited 1h ago
They don't prescribe amphetamines for weight-loss/obesity; it's sometimes prescribed for binge-eating disorder. Which of course is because amphetamines suppress appetite losing weight is a side effect, but for weight-loss as a primary goal amphetamines aren't worth the addiction risk.
Edit: I stand corrected - I guess I presumed they were more restrictive with it nowadays but I'm sure it can be a good treatment for some
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u/Admirable_Form7786 1h ago
Nope.. they prescribe amphetamines fur wright loss all the time.. source, hundreds of weight loss clients in my dietetic practice
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u/Sweatybutthole 1h ago
My bad I was thinking about fda approval for Adderall specifically but there apparently are some brands which are approved for weight loss. Hopefully glp-1s continue to prove a more promising alternative with less risk
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u/CondescendingShitbag 2h ago
you got tapeworms and lost weight.
Lose weight AND get a new friend? Win-win!!
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u/mylizard 6m ago
This is funny to me because the scammers clearly didn’t care at all about the consumer’s health, but gave enough of a shit to provide a solution that might actually work instead of just putting baking soda or something.
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u/furtive 3h ago
I thought peptides lost something like 96% efficiency when travelling through the stomach. They figured it out?
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3h ago edited 1h ago
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u/gene66 3h ago
Taking the shot is no problem at least for me, my only hope for the pill is to make the shot cheaper hopefully
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u/brandontaylor1 3h ago
I was a bit nervous about doing injections myself, but the needle is so small I literally can’t feel it.
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u/tkw97 2h ago
Yeah I was hesitant to start because I can’t even look when I’m getting vaccines or blood drawn, but insulin needles are so tiny you barely feel anything and they don’t even make you bleed
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u/pichael289 2h ago
That's also due to where you inject it, I assume the abdomen? I've been a diabetic for 20+ years and there is something you can hit (like lymph nodes or whatever, I don't know) that will bleed pretty badly. But the needle is tiny so it's not gonna be a lot. It's happened maybe 5-10 times for me so pretty rare. I did have a CGM sensor (needle is a bit bigger and injects a long wire) that stared gushing blood once but that was one time. I simply avoid white shirts and it's not an issue
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u/alewiina 2h ago
95% of the time I can’t feel it, but this week I hit a nerve and it hurt SO bad. Thank god that doesn’t happen very often
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u/ZorbaTHut 2h ago
Fun fact: there are some wild semi-DIY solutions that make this much cheaper, if you're willing to feel like you're living in a cyberpunk setting.
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u/5150_Ewok 2h ago
Injections are absolutely the way. But I get people not wanting to stick themselves.
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u/pichael289 2h ago
I assume it's like an insulin pen, the needle is so tiny you literally cannot feel it. The only painful thing is if it's a large amount your injecting since (I assume) it just goes into the skin. Insulin is itself a peptide so I figure the process is similar.
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u/alewiina 2h ago
It is. I’m terrified of needles and I still give myself the shots no problem. Most of the time you literally don’t feel it, I always have to check and make sure it’s actually in because I just don’t feel it at all
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u/5150_Ewok 1h ago
It’s just an insulin needle.
Pinch and poke…rather easy but some people are afraid of needles so they justifiably won’t like the injection method.
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u/ChaoticSquirrel 1h ago
It's definitely not a lot of liquid! I think half a milliliter at my dose. Way less liquid than my humira injections used to be.
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u/JerryfromCan 2h ago
Ozempic has normalized self-administered needles. I think it will lead to better self treatment paths for people.
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u/xyonofcalhoun 2h ago
it's perhaps mainstreamed them but self administered subcut injections from a pen have been normal for a good while, especially for diabetics
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u/pichael289 2h ago
Pens are great. Actual syringes have to be long enough to get into the vial so I always worried I could go to deep and fill one of my kidneys with insulin. The pens you just stab yourself to the hilt.
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u/JerryfromCan 2h ago
Diabetes per Google is about 12% in the us. Ozempic I have heard is closer to 30%, so roughly doubled to tripled the uptake?
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u/MrHyperion_ 1h ago
No way almost one in three takes ozempic
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u/PhantomAngel042 34m ago
It's about 1 in 9 (11%) in US adults for all GLP-1 use, according to Gallup.
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u/ackermann 2h ago
How often do you have to take the pill? Weekly or monthly like the injections?
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u/alewiina 2h ago
There’s a monthly injection? Mine is weekly
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u/TehWildMan_ 2h ago
Pfizer has an early stage candidate for a once monthly candidate, but that's extremely early in development.
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u/imalanjohnson 1h ago
I can only speak for myself but it has absolutely worked for me and my use case. I am in my early 40s and have consistently been juuuuuust above the “obese” BMI number despite very consistent and vigorous exercise every weekday for most of my adult life. I would teeter 2-3 lbs up and down over the years except for a very strict and pretty miserable calorie deficit diet I did for about 8 months where I made serious but unsustainable progress.
Fast forward to mid July of this year where I started the wegovy pill. Since starting I have EASILY lost 10 lbs (3 months), with no change to my routine other than the smaller portion sizes and disappearance of cravings for sweets/snacks. I’ve been on two vacations in that time as well, which have also been much improved as I used to stress about keeping up with my workouts and would agonize over missing days because I felt like I was opening the door for major weight gain. So I would credit the pill with a huge improvement for my mental well being too.
Again this is very much my use case being ideal. Active lifestyle, very regimented early morning routine making a 30 minute fasted dose easy, and essentially no other factors contributing to my weight plateau other than cravings/food noise. But it definitely can and does work.
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u/jackloganoliver 1h ago
That's amazing! I'm so happy for you.
My MIL was super strict with her diet and exercise and struggled to lose weight too, and the injection has been great for her. I'm hoping my husband can see some progress too. I just want him to feel better about himself.
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u/level1hero 3h ago
They had to give them a good talking’ to in order to make them more efficient in pill form. It was a pep talk
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u/chux4w 3h ago
A peptic pep talk?
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u/entropicdrift 3h ago
A peptic peptide pep talk
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u/rkubiak 2h ago
If you’re walking while giving the talk, it’s a peripatetic peptic peptide pep talk.
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u/Hatted-Phil 59m ago
If you've just been arrested, it's a peripatetic peptic peptide perp walk pep talk
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u/terraphantm 3h ago
Oral semaglutide is mostly through brute force -- much larger dose and daily, and still not quite as effective. Lilly's Orforglipron is a small molecule rather than a peptide, so more readily absorbed.
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u/PhantomAngel042 26m ago
I'm excited about the prospect of the drug itself, but every time I read the word "Orforglipron" my brain gets a little tickle of amusement. Yes, I know it has to follow specific naming protocols; but it's such a stupid word, in the most delightful way.
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u/ateallthecake 3h ago
I have lost 50lbs on the wegovy pill after starting in February, after not being able to lose any weight since 2018. I set my alarm a little early, take my pill with a sip of water, and then by the time I wake up for real it's been over an hour and I can start my day with no consequences.
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u/TehWildMan_ 3h ago
Yes, additives like SNAC can help but you still lose a huge portion of bioavailability and there is a pretty strict requirement for food/drink fasting before/after taking it, since the additive causes absorption at the stomach, not the intestines.
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u/MagazineEnough3792 3h ago
Foundayo’s bioavailability is 78% vs oral semaglutide’s 2%, which is why there’s no water or food restrictions around it.
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u/MagazineEnough3792 3h ago
Foundayo is a non-peptide and does not degrade in the stomach, unlike oral semaglutide. That’s why you can take it anytime, anywhere. Foundayo is the real deal.
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u/sk1nnyjeans 3h ago
I know of various pill form supplements that have a coating, protecting them from being deleted in the stomach. I’ve purchase probiotics with such coatings before.
Maybe it’s a similar approach.
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u/flip6threeh0le 3h ago
They overdose the pills to account for it. Side effects and costs go up
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u/ChaoticSquirrel 1h ago
costs go up
The pills are cheaper.
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u/flip6threeh0le 1h ago
Maybe overall. But not on actives. And not sure all that coat is passed along to the consumer
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u/ChaoticSquirrel 46m ago
The Wegovy pills are $299 a month for the highest dose, and $349 a month for the comparable dose of injections (injections go to a higher dose equivalent). So yes, the cost savings are at least somewhat passed onto the consumer, which is what I think you were trying to say.
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u/SqueezyCheez85 1h ago
Why would side effects go up? It's my understanding that the body just flushes it out quicker. Should be same amount of drug in your bloodstream... Right?
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u/Anal_Herschiser 46m ago
Makes me wonder if you could reconstitute the pills back into shot form for higher dosages.
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u/mega_douche1 3h ago
What's the benefit then
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u/BonzBonzOnlyBonz 2h ago
Its significantly easier to get someone to take a pill compared to getting stuck with a needle.
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u/TehWildMan_ 2h ago
Convenience.
Although it still has to be taken fasting since it's absorbed through the stomach, not the intestines, and it's daily instead of weekly.
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u/re_nonsequiturs 3h ago
They weren't scams back when fenphen was a thing either
They just didn't mention the bleeding
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u/Theguest217 29m ago
Don't worry, we will circle back and a few years for the class action Ozempic lawsuit
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u/--tc-- 3h ago
They still work because they reduce the amount that you eat. The "diet pills" usually claim to burn calories which usually isnt true. And the ones that do increase calories burned arent all that safe or side effect free (DNP)
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u/BlunderIsMyDad 3h ago
Stimulants fat burners increase calories burned by a useful amount, and cause appetite suppression. The body just adapts to these effects within a couple months of daily use, and can even become physically dependent so they're an awful fit for long term weight loss. Also, the safest and most evidence based ones are caffeine and EGCG which both are found in green tea (and are otherwise cheap in pill form), so spending the $40 a month on anxiety powder is not something almost anyone should consider.
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u/AN0NY_MOU5E 3h ago
The pills advertised in magazines were stimulants. You might have a heart attach in the process but with enough stimulants you will lose weight.
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u/kadunkulmasolo 2h ago
I'd rather have a heart attach than a heart detach though.
I'll find the door myself.
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u/TexasAggie98 2h ago
There were some that were actually tape worm eggs. People would lose weight (but had some other mega side effects…).
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u/pacnwcub 3h ago
I mean those ads are still scams. Having GLP-1s in pill form now doesn't magically make those old scam pills no longer scams.
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u/IncomprehensiveScale 3h ago
what OP is saying is that the ads you see NOW aren’t scams. it’s the same style of ads, but they’re not scams anymore.
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u/Stevied1991 3h ago
People are way too comfortable being assholes to other people online these days.
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u/gliitch0xFF 3h ago
Its no coincidence that the asshole is the first thing to be created in the womb, some just don't grow beyond that point.
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u/IBJON 3h ago
How does it feel being illiterate?
OP specifically referred to
those "Take this diet pill and you will lose weight!" advertising scams in magazines back in the day
meaning, they're not referring to modern ads or ads that we may see in the future.
As written, OP's statement is incorrect and the person you replied to is correct
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u/nimajneb932 2h ago
Those pills weren’t scams, depending on how far back you go. In the 90’s and early 2000’s they sold some with ephedra and other heart pounding drugs. Ephedra was just legal meth at the doses people started taking.
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u/AngusHenley 2h ago
My mom took them in the late 70s and immediately quit because they scared her they were so powerful
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u/TheDollarstoreDoctor 1h ago edited 1h ago
I get Ephedra behind the counter (bronk aid) and at the dosage they sell it in now, I would say yohimbine is more uncomfortably speedy. 100 mg of Ephedra doesn't come close to it, and you can buy it on Amazon! Crazy!
Now I take fake ephedra from the vitamin store and it's speedier than both combined. Yes I make bad decisions but I used to be a big back and needed that weight dropped stat. I have this weird fear that GLP1s will make me shit myself, I can handle heart palpations but I draw the line at gastrointestinal distress
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u/genesiss23 4h ago
Semaglutide has been available in tablet form since 2019 as Rybelsus in the US. It just never was as popular as Ozempic injection. Wegovy tablet was approved in 2021.
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u/MrFlow 3h ago
Well i don't live in the US and it hasn't been approved until recently here.
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u/lithaborn 3h ago
I've been on rybelsus in the UK for 2 or 3 years. Did ok for my A1C, didn't do a thing for my weight.
My diabetic consultant put me back on injections 4 months ago and it's so, so much better.
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u/SoggyWotsits 3h ago
Not a problem in the UK. Adverts for all prescription medications are banned.
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u/CoffeeFox 3h ago
Diet pills in previous decades actually worked, but they were stuff like ephedra, which was similar to taking meth to lose weight. In fact you could manufacture meth from the ephedra plant.
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u/JesusDoesntLoveu 3h ago
And one day, we'll be able to say the same thing about all those penis enlargement pills advertisements.
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u/SpaceShipRat 2h ago
that'd be fascinating. I wonder how it would improve society when certain individuals can cure their insecurities
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u/Dr_Insano_MD 1h ago
Sort of. GLP-1 just makes you feel less hungry and makes you full faster. You still have to actually eat at a calorie deficit. It just makes it easier to do so. You can still end up in a surplus from calorically dense foods.
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u/battlepi 34m ago
It definitely does more than that. Metabolic adjustment seems likely. I don't think they've figured it all out yet.
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u/SPOOKESVILLE 6m ago
It reduces the hormones that cause hunger. It COULD do more, sure, but there’s not much of a reason to claim that at the moment, we have a decade of research behind it
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u/drako_86 2h ago
Most insurances do not cover it. Even the ones that do tend to only cover if you are severely obese or diabetic. Being anywhere in the yellow or orange range on the BMI scale will have most doctors saying no because insurance
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u/im_a_goat_factory 1h ago
It’s pretty cheap now though, at least for the needle form
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u/GenTrapstar 1h ago
What’s cheap now?
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u/im_a_goat_factory 1h ago
75 a month or so
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u/GenTrapstar 48m ago
For what? Cause for me ozempic with insurance is $165 a month. Wish I could pay $25-$75 a month.
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u/HisCromulency 46m ago
My insurance doesn’t cover and Wegovy 2.4mg would cost $350/month
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u/GenTrapstar 27m ago
Shit is crazy cause I’m not sure what insurance some people have but they are literally able to get this ish for $25 a month. Like that has to be the golden insurance to have. Sad part is mine is literally for diabetes’s and yet I’m still paying an arm and a leg.
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u/im_a_goat_factory 22m ago
My wife got it going for both of us. It comes in a vial and it’s a shot into the belly. We don’t use insurance for it. We used an online doctor
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u/im_a_goat_factory 13m ago
Ok I just had her check so it’s the drug that starts with the T, we buy highest mg for 3 months at $150 a month and then we split the medication. So that’s where my 75 a month came from
150/mo is still pretty cheap when you factor in how much money you save on food and alcohol lol
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u/DizzyMine4964 3h ago
No. The latest scam which I've seen on Android games is "weight loss patches", supposedly coming from a big pharmacist in England (because I'm an England). All AI. Complete and utter scam.
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u/ImGCS3fromETOH 1h ago edited 8m ago
If you're buying them out of the back of a magazine they likely still are scams. Being in pill form doesn't change the fact you need a prescription.
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u/FleshlightModel 42m ago
I love GLP1s for the wider sedentary layman, but being interested in bodybuilding, they're absolutely horrible. They deplete your sarcoplasmic volume which will leave you flat and stringy (opposite of what bodybuilders need), and zaps your liver glycogen stores which will act as a brake if you are going hypo. Yes I know that is a very niche population but there are a million other drugs or supplements that are better for fat loss in that population, including the old ECAYN stacks from the 90s (maybe even 80s?).
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u/goddessnoire 3h ago
Just to give some info since I take a GLP1 myself, the pill that most people are referring to is the Wegovy pill. It is not the same as previous pill forms of weight loss drugs. And it’s still very expensive. And the rules are strict as to how to take the pill. It needs to be taken with very little water, and you cannot eat or drink anything or take any other medication within a half hour to an hour of taking the pill. Personally, I do not think that it’s as effective as the injections, but people still can lose weight taking the Wegovy pill.
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u/Pandoras_Fate 2h ago
I started with the pill and it was useless. Switched to the shot and dropped a dress size in two weeks.
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u/Few-Counter7067 1h ago
Weren’t the ones in the 90s and earlier just speed? Like they did work but not as intended.
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u/SatanDarkofFabulous 50m ago
The pills are waaay less effective because they have to go through the liver so arguably, still a scam
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u/PhysicalConsistency 16m ago
The ads in the magazines were exploiting the real diet pills being banned. When we could get cranked to the gills on stimulants, it was pretty easy to create a calorie deficit by reducing calorie intake and increasing activity. They took cocaine and tried to sell us diet coke as a replacement.
We also had Contrave available for quite awhile before Foundayo/Wegovy, but it sucks for most people and isn't terribly effective outside of clinical studies.
The shots are still much more effective, and the triple/quadruple action meds coming out next year and 2028 absolutely smoke gastric bypass/lapband surgeries.
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u/classicman123 3h ago
It's not that simple. It tells the brain to stop binge eating. A normal sized portion is enough. Some people with other addictive habits have even reported a decrease or a complete cessation of those bad habits, such as drinking, smoking etc. It's almost as much of an addiction pill as it is a weight loss/diabetes pill.
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u/goddessnoire 3h ago
GLP1s aren’t scams. There is a multitude of research and evidence to show that people actually lose 20 to 25% of their body weight taking this medication. I’ve been on Zepbound for 19 months and lost over 100 pounds. There’s no way I would’ve been able to do that by myself without medication. I still diet and exercise, but it’s made a hell of a lot easier.
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u/zytz 2h ago edited 1h ago
The thing is, if you don’t change anything about how you eat or live your life the medications don’t help you lose weight. The laws of thermodynamics still exist
Edit: I keep getting a lot of similar comments about how the way these meds are intended to work is by modifying gastric emptying, which in turn makes you feel full, effectively ‘forcing’ a lifestyle change by making you eat less. Ive been on GLP 1 meds for coming up on three years, i understand the science and its intended mechanisms, and all I can say is that while I agree in theory, in practice it’s not that simple for everyone.
I spent 2.5 years on semaglutide and had an initial 5-10lb loss, but by the end was 10-15 lbs heavier than when I started. I have since changed doctors to a metabolic specialist, and changed drugs to tirzepatide, and now finally understand what delayed gastric emptying feels like, and finally also understand how it feels physically impossible to put more food in my body.
Unfortunately, nutrition, metabolic pathways and the diseases that affect them aren’t a perfect science, and real world patient populations often have more complex medical histories than those accepted into studies about these drugs that can in turn affect how their bodies respond to these drugs.
I’m not intending to scare anyone off these meds, far from it- I think they’re an incredible bit of pharmacological innovation that’s achieving incredible things. But there is nuance here, and I think calling them things like ‘magic pills’ is a disservice to everyone
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u/BetterDrinkMy0wnPiss 1h ago
These medications force you to change the way you eat. You literally can't eat the same volume of food while you're taking them, that's why they work.
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u/how_can_you_live 2h ago
You will get violently ill if you continue eating the volume of food you are used to once started on semaglutide / tirzepatide / retatrutide (assuming the medicine is prescribed for obesity, but still in part applies for blood sugar control).
Gastric emptying is massively slowed down, so not only will your digestive tract “fill up” with food faster, but it will also stay in the digestive tract for longer; so you’ve essentially slowed down the conveyor belt and if you keep stacking boxes, it will throw them all back out.
So what you said is correct, but no, you are physically unable to continue bringing that same number of calories in.
The helpful side effect of that is your body doesn’t produce as much ghrelin, which is the hunger signaling hormone, once you’ve started on a GLP-1. That is what makes the cravings go away, and in part, ensures your “adherence” to the medication.
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u/zytz 1h ago
What you’re describing is not a universal experience by any means. I’m about to enter my third year on these medications, and for nearly all of the time I felt almost no difference at all on semaglutide. I still had uncontrollable cravings, I was still prone to binge eating. I’ve been eating an extremely healthy diet for many years now, and aka good deal more active than your average person, and I would say that exceptionally active compared to most folks with my level of obesity. But for about 2 years the needle simply didn’t move because I would still overeat a lot, and regularly. And over the final half year I actually gained 10-15 lbs.
A little under four months ago I switched to tirzepatide, and since then I have had the experience you described. I have very acutely felt the related gastric emptying on this drug, and especially early on it was so pronounced I couldn’t even manage 1000 calories some days. The degree of disinterest I have in food has been a completely novel experience for me, and a night and day difference from my experience on semaglutide.
But what you eat matters a lot as well. I struggled to get 1000 calories in because I was already eating really clean like 85% of the time, and cleaner foods are simply less calorie dense, generally speaking. I would have to eat an obscene volume of food to make 2500 calories (my maintenance when I started) daily. But for someone with a much more average American diet? Like starting your day with a sugary creamy coffee, fast food for lunch, salty packaged snacks and sodas during the day, carb and red meat heavy evening meals. Folks like that could easily reach 2500 calories by lunch on a pretty low volume of food, if they ate the way they normally did. I can’t speak to what those folks experience because I haven’t eaten like that for decades. I know I personally feel ill like you describe if I eat badly, but I’m pretty sure that would also be the case if I weren’t on tirzepatide.
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u/Bad-Luck-Guy 1h ago
I ate huge volumes of food before the Wegovy pill. Mostly from fast food and restaurant meals. Easily hit 2500-3000 calories a day. Now I have to be very intentional to get over 1000. Zero interest in food. Even eating healthy makes me full super fast.
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u/GingerScourge 1h ago
As someone who just started one of these magic weight loss pills, at least for me, it’s physically impossible not to change how I eat. If I ate my before Wegovy portions, I’d feel sick all day, and probably be making runs (pun intended) to the bathroom every 15 minutes. The cravings are gone. When I used to have difficulty leaving food on my plate, I couldn’t finish if I wanted to now. That’s what these medications do, they change how you digest and how you perceive food. And with only taking the pill and eating how the pill makes me eat, I’ve lost 22 pounds in 5 weeks.
So, your statement, while technically correct (if you don’t change how you eat they won’t work) the reality is, you aren’t correct because that’s exactly what the medication makes you do. Change how you eat and your habits around food.
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u/psu256 1h ago
Supposedly food is supposed to take 24+ hours to pass through your system. Mine rarely survived in there for 4, clearly mostly undigested. Ozempic finally has slowed things down to what is considered medically appropriate and it absolutely has changed how I eat for the better. My stomach was emptying itself so fast it was always demanding more and you can only ignore that distraction for so long.
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u/zytz 1h ago
I’m really glad for you, but I was on semaglutide for 2.5 years and never experienced any of what you described until I recently switched to tirzepatide. The pills aren’t magic, and they can and do affect people differently. I’ve got an obese friend that had a similar experience to me on semaglutide, and continues to have that same experience on tirzepatide. She also has some other things going on medically that might just be affecting the efficacy of these medications for her.
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u/MacDugin 1h ago
You still get the same pains and symptoms as you over eat but worse. It teaches (forces) you to eat better.
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u/jroberts548 1h ago edited 1h ago
this is technically true.
if you take a glp 1 and both want to and are able to eat as much, something is very weird with how your body is reacting.
It also helps metabolism. A problem people run into with calorie deficit diets is that their metabolism slows as their intake drops. The basic calories in-calories out math is complicated by not burning calories at a consistent rate.
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u/QuickProfessional101 1h ago edited 1h ago
Nah man. You literally order a medium pizza at a restaurant and take half of it home because you can't fit more than 2 slices. Before you'd eat 2 large pizzas + mozzarella sticks and ordered dessert. And instead of eating burgers and kebabs and shit you'll start craving salads, fruits and the portion sizes that you thought were already tiny a year ago are now 20% smaller and just right/a little too big.
Airplane sized stuff is perfect right now. It's even a little embarrassing to eat like a skinny white chick from 2000's TV shows and i have to pretend I just ate and will just order a fillet mignon as a snack instead of a huge ribeye.
It's literally magic. Expensive magic. Best 500/month money I've spent. ZERO effort to lose weight if you don't count crying when looking at the credit card bill.
Most people buy the fake stuff or don't inject it just in the right spot at the right angle at the right dosage.
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u/tourniquette2 3h ago
Time will tell. They touted phen phen as a miracle drug too. Then it was the hcg diet. There’s always a chemical. And it takes a few years but the side effects show themselves and then there’s class action lawsuits that follow.
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u/allbusiness512 3h ago
At least in the injectable form GLP-1s have not had any major side effects to them. They've been in use for off label use for decades now. Too many people are ignorant about the history behind them. They are at the end of the day used as predominantly diabetic medications.
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u/nanadoom 3h ago
Except acute kidney injury and pancrreatitus
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u/allbusiness512 3h ago
Every medication has side effects, we have been studying GLP-1s for decades now. You can literally overdose on advil for crying out loud.
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u/DorkusMalorkus89 3h ago
GLP-1 meds have been in use since the early 90’s, they just weren’t marketed specifically for weight loss like they are now. If there was any major side effects or scandals related to this medication, it would have happened already.
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u/nebraskajone 3h ago
The previous weight loss drugs failed because the body always figures out a way to compensate. When you start losing weight your body does everything it can to stimulate your appetite.
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u/zappergun-girl 3h ago
I’d love to get on this magic pill to help with these last 20 lbs, I’ve been stuck for a long time. But my fear of unknown side effects down the road is stronger. Just feels unfair that doing things the old fashioned way isn’t working for me
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u/allbusiness512 2h ago
Honestly just do it. Go with a reputable source (either through your insurance, or compound which is still on a technicality legal) and it's 100% worth it. You save on the cost of food alone.
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u/joshBigHockey 2h ago
Yea unless it turns out peptides cause some devastating disease or cancer after years of extended use.
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u/ChaoticSquirrel 1h ago
Good thing they've been studied since the 1990s and on the market for over 20 years!
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u/m3t4lm4n222 57m ago edited 28m ago
Yeah, but the uneducated idiots who like to spread FUD about anything they don't have the intellect to understand will just come up with another excuse to disregard that.
They'd much prefer we keep things the way they are. 40% of the country obese, over a third of adults prediabetic, people losing toes and feet to diabetes. That's the *natural* way. Because everybody knows the only real way to lose weight is willpower, chicken and broccoli, and 5am cardio. If that doesn't work for you, you obviously just didn't want it bad enough and you've earned your metabolic disease. Lost 50 lbs on a pill that mimics hormones your gut already makes after years of nothing working? Doesn't count, that's cheating.
Imagine if these same people were around in 1922. “Insulin? Some peptide squeezed out of cow pancreases that they want to inject into kids? No thanks, I’ll manage my type 1 diabetes naturally.” Before insulin, that diagnosis was a death sentence. And fun fact, insulin is a peptide too. These are the same people who would’ve laughed at Semmelweis for telling doctors to wash their hands.
There are legitimately people who will read things like this - or do the research, get the information, etc - that have too much pride and ignorance to admit they were wrong and change their stance.
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3h ago
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u/godzillachilla 3h ago edited 2h ago
Weird gatekeeping going on here but ok.
Is it in short supply or something that I'm not aware of?
Edit: I was being facetious. There's not a shortage.
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