If I’ve got that rebound effect going on I’m just gonna go make myself puke, pound some pedialyte, take some ibuprofen, and pass out on the floor by the shitter. Otherwise the next days gonna be ruined lol.
Don't start with "it's actually perfectly safe", essentially medical advice, if you're unconfident enough to say "correct me if I'm wrong" lol. Yes you are wrong. Ibuprofen and alcohol puts you at risk of stomach ulcers and other stomach/intestinal distress as well as kidney damage, and it will warn you of this on any bottle of ibuprofen. And Acetaminophen is not an NSAID. You're correct that acetaminophen more adversely affects the liver, though.
Not saying it's deadly or even that I've never done it but "perfectly safe" is a little bold
Another small bit of info, acetaminophen isn't an NSAID! For those who can't take NSAIDs (like myself), tylenol is the only safe painkiller pill that's readily available. NSAIDs are really rough on the linings of your digestive system iirc, so if you're at a risk for bleeding it's not wise to take them, I'd think alcohol only makes that risk worse.
It has to do with metabolites. Your body breaks stuff down by making small changes to the molecules using enzymes. There's usually a few steps in this process. The molecule has several small changes applied to it until it's turned into something you can either use, or pass through into your waste.
These consecutive small changes are called metabolic pathways.
Well, sometimes the enzymes that are used in these reactions get saturated. That means they're all currently busy turning one substance into another. Alcohol is really good at saturating it's pathway because it's consumed in large quantities compared to basically any other drug.
Sometimes, when a pathway is saturated, a different pathway can be used to metabolize the same drug. Ultimately, the enzymes are looking for certain structures within a molecule. They're not necessarily positively identifying one whole molecule vs another. So other enzymes come in and make a different change to the molecule, which sends it down an entirely different pathway.
This is what happens between alcohol and acetaminophen. Alcohol comes in and hogs all of one enzyme, which causes acetaminophen to be metabolized by a different enzyme than normal. The product of that metabolism ends up being highly toxic to the liver.
At least, that's how i remember it. It's been a while since I refreshed that information, so it may have become warped or conflated over time.
Another fun fact that's a part of this: Alcohol can be used as an antidote for antifreeze poisoning. The reason antifreeze is poisonous is because of a toxic metabolite that's created as a part of its normal pathway. Alcohol hogs that pathway, and slows down the metabolism of the antifreeze (ethylene glycol) so that the waste product is created more slowly, and thus can be cleared before it builds up.
I had trips off a DMT pen where this type loop has actually happened. Didn’t like those trips cause at times you would actually get stuck in the loop for a good minute or two and would start getting scary.
This was my go to in college. I’d always wake up needing to pee at 6 am a little hungover then drink more water and wake up at 10 feeling pretty decent. Meanwhile my friends who drank the same or less than me would be feeling it
There was always a 50/50 chance that this would happen with me.
Let's say one day I drank six 25oz beers...no puke slight hangover, some other day I'd drink the same amount (6) then I'd puke and be nauseous for the better part of the day.
After you lay down, let one foot touch the ground and it should stop the spins (so lay flat on your back with one leg on the bed and one draped over the side with your foot on the floor. UNLESS you're vomiting drunk, then don't lay on your back)
This trick never did absolutely anything for me. What does work for me is lying face down with my stomach slightly suspended in a sort of semi-plank position aided by the pillow until I fall asleep.
Honestly I’m kind of locked in, legs locked around my guy and it feels like I’m on drugs. There is no feeling like it. I’d only feel sick if I’ve mixed spirits or drank too much but they’re entirely separate feelings. I guess I’m lucky. I hope you don’t feel sick next time.
that’d make me nauseous immediately. This is why I never get this drunk anymore I get sick too easy. Also weird, I get sick every time I get crossed with weed, even a lil. ain’t it supposed to be opposite?
I remember from when I smoked a whole lot of weed that for me it always depended whether I smoked or drank first. if I drank first and then smoked I was feeling like everything around me is spinning and it was so freaking bad. when I smoked first and then drank everything was okay.
Honestly it's the part of being drunk I enjoy the most.
The sheer joy of drunkenly falling into my bed and knowing I'm going to be incredibly comfortable and asleep in less than five minutes. The complete lack of fucks to give.
As a lifelong insomniac, there has never been a better sleep aid than a decent drunk sleep and so long as I don't overdo it, I wake after a full 8 hours of sleep and happy to meet the day.
I totally get that, but I think that the feeling of the room and ceiling twisting and turning (when I'm that far gone) puts me into a little panic until it finally fades and the comatose sets in. Those nights that I had back in the days, laying down, seeing and feeling the vertigo were some of the worst nights for me in the moment. I look back on them now and laugh, but in the moment that shit is fucking terrifying for me. Like bro, I made the choice to go to sleep now, please just let me fall asleep. 😂 But I reaped what I sowed, so we ball.
My guess: your body recognizes that whatever is touching the bottom of your foot is "down", so your body now has a point if referenceto maintainits sense of direction/placement
When we are drunk, we loose balance, thats an ear/brain job. When you put 1 foot on the floor, you regain balance in your brain. Thats why we tend to stand up when we feel this fuckery effect.
Not an expert, but I'm pretty sure it just gives your brain a point of reference. You can overcome motion/sea sickness in a similar way, by looking at the horizon or something fixed off in the distance.
There's 2 type of people in this scenario. The people who enjoy it and fall asleep on a wild ride (not me). And the ones who get nauseas and just need to puke themselves to sleep (me).
The only way I could deal with this (when I used to drink), was to just keep my eyes open as long as I could before I passed out. 60% of the time, it worked everytime.
Interesting how alcohol collapses you into you, and psychedelics do the exact opposite. That is all. Just simply find the brain and whatever is going on to be quite interesting.
There was a guy on YouTube a while back who was a poly addict and took just about every commonly known substance as often as he could. He said that the most sick and poisoned he’d ever felt from ingesting a substance was from drinking too much alcohol.
Then drink 2 glasses of water and puke both of those up.
Then drink a third glass of water and eat a bunch of bread.
Then piss because you are now in piss yourself while you sleep territory since you drank so much water.
Now you can optionally sleep on the cool bathroom floor for an hour. If not, go to the next step
Pour some more water and leave it on your nightstand. Also, put a salad bowl there with some aklaselzer, a multivitamin, a bag of chips, a banana, and a box of OJ. For the next morning. If you can drink V8 juice, put that there too.
Once you wake up, consume whatever you can off the table. Then use whatever delivery service to order mcdonalds for the grease.
After the table is consumed, eat mcdonalds until you puke again or hold it down.
Now, drift in and out of napping for the next 4-8 hours.
This will not fix you, nothing will. But it will make you feel as good as you can. Everything i said is backed by science. The specific items are chosen for the vitamin and mineral content, as well as the macros.
Don't take fucking Tylenol. It will kill you if you still have liquor in your system. Look that shit up.
It’s odd, this used to be an almost pleasant experience after a long night and early morning of drinking, sort of a validation of my debauchery in my late teens and early 20s. But in my 30s, it produces an instant nausea so intense that I will just not sleep until I’m almost sober the next day, regardless of how tired my alcohol soaked brain is
The worst I had was a red wine drunk that had the spins. When they finally went away I was able to sleep, woke up a few hours later with dry mouth. Drank a whole lot of water and felt drunk again and once again had the spins had this happen a total of 3 time until morning. I want to say it was after the pats giant super bowl when the pats almost had a perfect season. Had a pitch of lits at the party was drinking Sam Adam's and personally drank a box of wine mostly to myself. (Don't binge drink kids I am lucky nothing terrible happened)
I hate to say it but I wish I could still get drunk. Because of the alcoholism and my narcolepsy medicine it's almost impossible to get drunk. Even after finishing a fifth.
I haven't had this sensation since before I was medicated.
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