r/Microbiome • u/Tummy-boy • 3h ago
Kimchi: does it really help with seratonin production in the gut
I bought some wildbrine kimchi and been consuming it daily. It is oh so spicy
r/Microbiome • u/Kitty_xo7 • Feb 22 '25
Hi everyone!
Thank you all for engaging in the r/Microbiome sub! This post is to notify everyone about a change in rules regarding GI maps, peddling services related to them, and asking for medical advice based on GI maps.
We will not be allowing posts asking for GI map interpretations from here on out (rule 7). Microbiome science is very much in its infancy, and we have very little understanding of how to interpret an individual's microbiome sequencing results. More specifically, we actually dont know what composition of microbes make up a healthy/unhealthy microbiome, both in presence/absence of microbes, and quantities of microbes. We know very little about the actual species within the microbiome. The ones we know more about are generally only more well studied only because they are easier to work with in the lab, not because they are more inportant. We have yet to culture most microbes in the collective human microbiome, meaning we also cant accurately identify many species via sequencing. There is also tons of genetic and functional variability within species, meaning we also cannot relate individual species to good/bad outcomes.
We also need to consider limitations of these tests. In as little as 24hrs, you can have a 100 fold change in many species. This means you can get incredibly different test results day-to-day, depending on many factors like sleep, excercise, diet, etc, within the last couple hours. Someone recently described microbiome testing as throwing a rock on the highway to predict traffic at all hours-- One rock wont tell us anything on the grand scheme of things. To be frank, these tests are also very cheap in their actual sequencing. Many of our most important microbes are in low abundance, which cheap sequencing and poor analysis fails to identify. Additionally, considering your microbiome has hundreds of species and thousands of strains, cheap testing often cant accurately differentiate between species. It is quite common for poor sequencing to misidentify or mis-classify closely related species or even genus'. A common example is Shigella being mistaken for Escherichia, or vice versa.
Many of the values that the microbiome tests predict are "ideal" are also totally arbitrary. We see major differences between different quantities of microbes within you over 24hrs, you vs your family, local community, country, and continent. However, no ideal microbiomes have been found, despite millions being sequenced at this point. There is tons of diversity in the global population, but there is no "ideal" values when it comes to microbes in your gut.
Secondly, we will be banning you if you are peddling services to others via this sub. We are an open and free discussion about microbiome science, and we use evidence when talking about the microbiome. People who claim to know how to interpret individual microbiome maps are either not knowledgable when it comes to the microbiome, or are lying to you, neither of which makes them trustworthy with your health. We will not allow this sub to be a place where people are taken advantage of and lied to about what is possible at this moment in microbiome science.
Finally, we want to remind you that this is not the place to ask for medical advice. Chat with your MD if you are concerned, nobody on here is more well versed than they are on specific symptoms. They will treat you accordingly. If you are seeking help for specific microbes, such as H. pylori, this is something your MD can test for. These results are accurate and interpreted correctly (not the case for GI maps), and will be significantly more affordable than GI map testing.
We aim to be a scientifically accurate, evidence-based sub, that provides digestible conversations about this complex science. These topics are not in line with our values.
We look forward to having everyone respecting these rules moving forward.
Happy microbiome-ing! :)
r/Microbiome • u/kisforkimberlyy • Jun 29 '23
We stand with the disabled users of reddit and in our community. Starting July 1, Reddit's API policy blind/visually impaired communities will be more dependent on sighted people for moderation. When Reddit says they are whitelisting accessibility apps for the disabled, they are not telling the full story.TL;DR
If you've been living under a rock for the past few weeks:
Reddit abruptly announced that they would be charging astronomically overpriced API fees to 3rd party apps, cutting off mod tools for NSFW subreddits (not just porn subreddits, but subreddits that deal with frank discussions about NSFW topics).
And worse, blind redditors & blind mods [including mods of r/Blind and similar communities] will no longer have access to resources that are desperately needed in the disabled community.
Why does our community care about blind users?
As a mod from r/foodforthought testifies:
I was raised by a 30-year special educator, I have a deaf mother-in-law, sister with MS, and a brother who was born disabled. None vision-impaired, but a range of other disabilities which makes it clear that corporations are all too happy to cut deals (and corners) with the cheapest/most profitable option, slap a "handicap accessible" label on it, and ignore the fact that their so-called "accessible" solution puts the onus on disabled individuals to struggle through poorly designed layouts, misleading marketing, and baffling management choices. To say it's exhausting and humiliating to struggle through a world that able-bodied people take for granted is putting it lightly.
Reddit apparently forgot that blind people exist, and forgot that Reddit's official app (which has had over 9 YEARS of development) and yet, when it comes to accessibility for vision-impaired users, Reddit’s own platforms are inconsistent and unreliable. ranging from poor but tolerable for the average user and mods doing basic maintenance tasks (Android) to almost unusable in general (iOS).
Didn't reddit whitelist some "accessibility apps?"
The CEO of Reddit announced that they would be allowing some "accessible" apps free API usage: RedReader, Dystopia, and Luna.
There's just one glaring problem: RedReader, Dystopia, and Luna* apps have very basic functionality for vision-impaired users (text-to-voice, magnification, posting, and commenting) but none of them have full moderator functionality, which effectively means that subreddits built for vision-impaired users can't be managed entirely by vision-impaired moderators.
(If that doesn't sound so bad to you, imagine if your favorite hobby subreddit had a mod team that never engaged with that hobby, did not know the terminology for that hobby, and could not participate in that hobby -- because if they participated in that hobby, they could no longer be a moderator.)
Then Reddit tried to smooth things over with the moderators of r/blind. The results were... Messy and unsatisfying, to say the least.
https://www.reddit.com/r/Blind/comments/14ds81l/rblinds_meetings_with_reddit_and_the_current/
*Special shoutout to Luna, which appears to be hustling to incorporate features that will make modding easier but will likely not have those features up and running by the July 1st deadline, when the very disability-friendly Apollo app, RIF, etc. will cease operations. We see what Luna is doing and we appreciate you, but a multimillion dollar company should not have have dumped all of their accessibility problems on what appears to be a one-man mobile app developer. RedReader and Dystopia have not made any apparent efforts to engage with the r/Blind community.
Thank you for your time & your patience.
r/Microbiome • u/Tummy-boy • 3h ago
I bought some wildbrine kimchi and been consuming it daily. It is oh so spicy
r/Microbiome • u/Sidonie75 • 17h ago
Hi! When I moved to the US from Europe, I noticed that eating raw onion made me fall asleep after 10-15 minutes. Like narcolepsy, I sleep 20-30 minutes and when I wake up it feels like a hangover migraine. I feel groggy and sad. Sautéed onions, leaks, spring onions, shallots and raw garlic have the same effects with varying degrees of tiredness. Because of that I avoided all alliums as much as possible which made it very difficult to go to certain restaurants or to eat at workplace catered events. I was the difficult one at friend’s dinner parties. Also some restaurants don’t mention onions or chives because it’s like salt or pepper to them. I’m grateful I can cook!
Painful for 15 years. One day by accident I realized that if I drunk kombucha, it could lessen the symptoms. Doing more research, I read somewhere that apple cider vinegar (ACC) might help. One tablespoon or I take 2 ACV pills before the 1st bite works like a charm!
I wonder if people may have a clue of what is at play in the microbiome. How do you explain this?
r/Microbiome • u/Quirky_Bat_9281 • 5h ago
Okay, hear me out. I’m not saying that everything is gut-related, but I strongly suspect there’s a connection.
I’ve seen four alternative practitioners, and pretty much all of them were useless.
I’ve had gut issues all my life, which were also influenced by my CPTSD and unhealthy lifestyle choices. I grew up around mentally ill people and was kidnapped as a child. I’m mentioning this because my early experiences had a significant impact on my lifestyle and eating habits.
I ate tons of sweets, consumed a lot of dairy, and drank 1.5 litres of Coke every day for 10 years. I feel like this must have taken a toll on my gut health.
I was eventually diagnosed with lactose intolerance (but tested negative for fructose malabsorption).
Stool tests didn’t detect H. pylori, but they did show low levels of lactobacilli, despite having taken probiotics for years.
In 2021, I changed my diet: I gave up gluten and dairy, drastically reduced my sugar intake, and started eating mostly freshly prepared meals.
Despite all these changes, I’m still struggling with gut issues and histamine related problems, particularly when my allergies flare up.
I’ve been wondering whether it could be SIBO, although I never experience significant abdominal distension or a noticeably swollen belly after eating.
I know there’s no quick fix, and I’m not expecting one. But it’s frustrating, especially because I also struggle with allergies and hay fever.
Has anyone experienced something similar or found a way to get to the root of their gut issues?
r/Microbiome • u/Sad_Glass_9521 • 14h ago
Currently despite the fibre I consume my stools are soft and can be messy to wipe. It then leads to feeling of stickyness around the anus a few hours later after wiping.
If my stool is really well formed and takes 1-2 wipes then things are good later in the day.
This has been ongoing since early 2025 and I havent been able to figure it out - even though I get fibre from my diet but also have 2 x 5g doses of NOW psyllium husk powder each day.
Then I read someone elses post that they think metronidazole has messed up their gut microbiome. I have diverticular disease and I have had this antibiotic lots of times in the past, once in 2018, once in 2021, once in 2023, once in 2024 but quite a lot in 2025;
January 2025: One week of metronidazole.
April 2025: bowel and anal symptoms began.
May 2025: Another week of metronidazole.
July 2025: Intravenous metronidazole and ciprofloxacin, followed by a week of both orally.
September 2025: Another week of metronidazole
October 2025: Colonoscopy
I havent been taking any probiotics as it wasnt until now that I have thought that this may be linked/the cause.
My doctors have prescribed me 4g colestyramine which I have been taking once per day for the past week or two which has made things mildly better. This was prescribed as I have gallstones too and they thought I may have bile acid malabsorption so this is a trial.
Is there any thoughts about whether 4 courses of the anti biotic in 2025 (the last being over a year ago) could have caused this issue that I am still dealing with now? And if so what I can do to help?
Thank you
r/Microbiome • u/ThePornStar69 • 15h ago
I had a gut bug (food poisoning) and a few weeks after that I developed severe 10/10 brain fog. The only thing I really changed between these two events was adding a ton of probiotics. This was 2 years ago now, and I haven't recovered.
The fog (drunk/high feeling) is constant, doesn't fluctuate - which is the most confusing part of it being gut related - and can flare a little bit higher sometimes with sugars or probiotics, but the baseline is always severe. I've tried all sorts of probiotics, antibiotics, fibres, diets (paleo, low fodmap, etc for at least 2 weeks each), I've even done a few day fast and nothing at all improved. There is no movement or pattern in the fog, as it's always present.
I've had all the common blood work I've seen in this sub, seen a few GI docs, had gut testing, and all has been perfect. I did had SIBO and resolved that.
I even tried some of the long COVID/CFS brain fog treatments like nicotine patches, antihistamines, low dose naltrexone, guanfacine, and none of it helped. I had COVID about 7 months before the food poisoning, so I'm sure it's not that anyway.
Does anyone have any ideas to pursue with my doc next? They're out of ideas and I'm stuck not being able to earn an income for my family.
r/Microbiome • u/QueenClarion777 • 18h ago
So about two months ago I was diagnosed with BV and the urgent care doctor prescribed me with metronidazole. I did not know anything about this medication and they didn't tell me anything about it even though it is an extremely potent antibiotic that wipes out all of your good gut bacteria. I was on it for one week and a couple days after my last dose I noticed that I felt very bloated and distended. As the days went on the bloating got worse and I felt like I had pockets of gas trapped along my large intestine. It is now two months later and I am still extremely bloated and have been experiencing slight changes in my bowel habits. My doctor has put me on two different pro biotics but I'm just worried that I will be stuck like this forever since I haven't noticed any real improvement. I know it can take up to 6 months for your microbiome to fully rebuild itself but it feels permanent. This has completely taken over my life and I am uncomfortable 24/7.
Idk if it is worth mentioning that I was also on Accutane at the same time as the metronidazole and I know that that can also cause GI problems. I have since stopped taking the Accutane and it hasn't gotten better.
I got ultrasounds and xrays done and everything looked normal and according to my doctor and everything I have researched, I will go back to normal. It just doesn't feel that way since this has been persisting for 2 months.
r/Microbiome • u/hypnoghoul • 3h ago
Hi, my situation is really hard to explain and a bit complex but I’m but sure how to go about getting help from my doctor or gyno. This has been ongoing since 2021.
Starting February of 2021 I woke up with a sharp cramp in my right ovary. I took a Tylenol then I felt better and went about my day, however I started having pain and itchiness, and I thought it was BV or a yeast infection. However this is when my symptoms became very odd, with this yeast infection I started getting bloating, nausea, fevers and hot flashes and cramping and fatigue. The symptoms didn’t let up and I felt sick for 2 months. I went to planned parenthood, got a basic exam, was tested for BV, yeast and STI’s and UTI’s. I was treated for BV with a cream. Symptoms didn’t go away. I was then treated for yeast with a cream. Still symptomatic, the itchiness and irritation in my actual vagina was gone at this point but I still had a burning acidic feeling in my uterus but it was not period pains and was outside of my period.
I got an ultrasound ordered from my doctor and they found absolutely nothing
My only form of treatment was eating raw ginger and eating a stupid amount of yogurt.
In May of 2021 I got sick with unrelated autoimmune symptoms which gave my body a break from all of this mess just to deal with something else, and then I got a Covid infection in Jan of 2022 and dealt with long covid for 3+ years and going on today.
My long covid improved then suddenly in October of 2023 I was hit with the previous symptoms but with a vengeance. My abdomen felt like there was acid dripping in it, I had no appetite, I was bloated and severely nauseous, the inflammation was messing with my vagus nerve and I basically was non functioning. This would happen before my period and my only relief was when my period came and I bled to reset my hormones.
Since then I started suffering with severe symptoms a week before my period, including fatigue that feels like narcolepsy, nausea, gi issues, inflammation, anxiety, depression, extreme cramping and joint pain and just feeling horrible and non functioning. I suspect PMDD or PCOS or endo at this point, but that brings me here today.
I finally have met with a gynecologist and he recommended to start taking my birth control continuously (Larin 24 fe) since my periods just make me sick. I have been on low dose birth control since I was 16 and I’m 28 now, but I would have a period.
So I did skip my period this week, and I felt ok, but today I woke up with my vagus nerve feeling tight, my vagina feeling irritated and dry, feeling very nauseous and bloated with no appetite and my uterus feeling like once again there’s acid being poured down it.
I am desperate to do anything to feel better and am begging if anyone else has experienced an overgrowth of yeast or a messed up PH or overgrowth of whatever that doesn’t just effect your vagina but also your mood and your stomach and microbiome. I am feeling depressed, hopeless and in pain.
r/Microbiome • u/StopThatDino • 5h ago
I’m wondering if there might be additional benefits to taking kefir in pill form.
r/Microbiome • u/That-Television-4856 • 19h ago
Mostly writing this just to rant so not really looking for advice, but it's still welcome nonetheless. I've had a pretty rough year overall with my health (a lot of headaches, anxiety, etc alongside stomach issues) and it feels like my poor tummy has just been destroyed from all of it.
I'd been having on and off stomach issues for a few years, but this year got prescribed antibiotics 3 times and had a few other things happen that were not good for my microbiome health. The first time was late last year, I got prescribed cefdinir for some sinus issues (it seemed like I was getting recurrent sinus infections). At the time I actually didn't notice any side effects, stomach-related or otherwise, but I think it was sorta the starting point of everything.
A few months go by, and I got sick with something. Idk what it was, but just general flu-like illness. Didn't have any COVID or flu tests so I just stayed at home and isolated till it was over. If it was COVID though, apparently that can mess with your microbiome, alongside everything else it messes up.
Then I got prescribed a second round of cefdinir because my sinuses were still giving me some issues. This time, however, definitely felt some side effects. My stomach got really, REALLY upset from the cefdinir. I also got prescribed a steroid at the same time and that made me really anxious too.
My stomach just seemed to be continuously upset after this to the point where eventually I went to the ER because my appetite was almost completely gone and I was getting some bad diarrhea. Got tested for a bunch of stuff, and actually was told for the first time here that my microbiome being messed up was likely the culprit due to the antibiotics, being sick, stress, etc. After this I started trying to eat healthier, and the stomach issues did seem to get better, but still didn't go completely away.
I ended up seeing a gastroenterologist and getting a colonoscopy. Ofc, that required the colonoscopy prep (which was a whole side-quest itself because I ended up having an allergic reaction to the first prep they gave me), which can also mess with your microbiome as well. Luckily though, the colonoscopy came back totally good, so no IBD, cancer, etc. Which also is part of why I think so many of my stomach issues are likely microbiome-related since so much else was ruled out already.
Finally, after all of this I thought I would get a good break to just let my body relax, but apparently not. Right before my colonoscopy I fell ill with a mysterious "flu-like" illness again that tested negative for COVID, flu, and strep and although I was mostly over it by the time I got my colonoscopy, I still didn't feel quite right for a while. When it got to be 3 weeks and I still was having some lingering cough and nose inflammation I went to an urgent care where, once again, I got prescribed antibiotics. Luckily the antibiotics did actually seem to help get rid of whatever illness I had, but once again they've made my stomach quite upset.
It just sucks because ever since initially having dysbiosis explained to me, I've been working hard on eating better and working on building up my microbiome to be healthy once again, but I've just had so many roadblocks. I'm glad I got checked for all the serious stuff with my colonoscopy (and endoscope too btw) but it's just annoying that my stomach is still all messed up after this. I'm slowly getting better I think, but it's such a long process, especially when you keep having things slow your progress.
r/Microbiome • u/Funny-Notice9392 • 1d ago
I eat a pretty healthy diet (high amounts of prebiotic fiber, inulin rich foods, resistant starches, no alcohol, no red meat, good mix of nuts/seeds/plants), however once or twice a week I like to eat out at restaurants. This could be something as simple as eating sushi, going to a local sandwich spot, or getting fast food (McDonalds, Burger King, and etc).
Will eating out and having a day or two where I eat somewhat poorly, negatively impact my gut microbiome? Or is the long-term consistent healthy eating more important than a day or two a week of poor eating?
r/Microbiome • u/iluvcee • 2d ago
Have had a relatively poor diet for most of my life + have had to take antibiotics quite a few times. I'm now eating healthier (35-45g of fibers daily) and have more whole food diversity in my diet, but I'm wondering if this is enough.
Specifically interested in increasing the levels of
Clostridium butyricum, Faecalibacterium prausnitzii, Eubacterium rectale, and Roseburia
r/Microbiome • u/Turbulent_Pay7404 • 1d ago
Hey everyone!
I’m looking for help and advice on what I can add to my routine or change to improve my health. I’m currently undergoing tests, waiting for appointments and results, but I’m also looking for some interesting insights from experienced people who are familiar with this topic. In general, I take good care of myself—I eat regular, balanced meals, drink plenty of water, and get plenty of exercise. I’ve always had great food tolerance; nothing ever caused me any problems until I went abroad, where I overindulged a bit for two days. Overeating led to mild food poisoning, a bloated stomach, a feeling of fullness, bloating, constant burping, and in the morning, mild diarrhea and passing gas. My stomach ached until the evening, but then I was okay, the next few days were fine—some mild diarrhea, sometimes worse, sometimes better—and other than that, nothing happened until the last day of the trip, when I was hit with terrible gas that kept coming out every few moments, smelling like sulfur or something rotten, and it went on like that for almost 24 hours. Then the problem went away; it ended with a bowel movement accompanied by diarrhea, and that was it—everything went back to normal. I went on with my life, carrying on as usual, sometimes it would come back a little, but not on that scale; I ignored it until, after a month, my condition worsened—it always ended up with me passing gas nonstop with that sulfury/rotten smell from after lunch all the way through dinner and after dinner, plus constant bloating; I didn’t have any other symptoms and still don’t, aside from those two. The problem persisted and continues to this day; sometimes it’s been better, and sometimes worse. As of now, I’ve been off Xifaxan for 3 weeks already. For 10 days, things were calm, though my motor skills were worse; later, the problem returned, but in a much milder form. Either way, it’s still there, and I’m not eating a normal diet, so I need to keep working on it. I’m sticking to a low FODMAP diet. Right now, I hardly pass any gas at all; if I do, it’s after a meal or in the evening. Before bed, I sometimes have 2–3 foul-smelling gases. My stomach rarely feels bloated, but it usually does happen occasionally. I sometimes experience constipation and some strange stomach activity, but it’s not the same as it used to be. Either way, I’d like to get better. Does anyone know what this could be? Where should I look for the problem? Helicobacter, parasites, complete blood count, B12, and ferritin are all within normal ranges.
I’m taking Iberogast, NAC, and L-glutamine.
r/Microbiome • u/timeline_longevity • 2d ago
A recent preclinical study uncovers Urolithin A's potential to improve gut health. Researchers from the University of Louisville found that Urolithin A activates a protective pathway in intestinal cells. In inflammatory bowel disease, triggering certain cellular pathways can cause more inflammation; however, in preclinical models, Urolithin A activated a specific pathway with a beneficial response. This activation strengthened the intestinal barrier, boosted production of protective mucus, and reinforced antimicrobial defenses. The researchers state it's the first study showing how a postbiotic can work with the body's own response systems, helping regulate complex processes that happen during intestinal injury.
r/Microbiome • u/TaxApprehensive5402 • 2d ago
I’ve been experiencing a lot of foul-smelling and loud gas, especially at night. My stomach gets really bloated, but I don’t experience any pain.
A friend suggested that I start taking fiber supplements around the same time as the probiotic I take before bed.
What types of fiber would you recommend? And what’s the best way to start?
I’ve read in a few places that it’s best to introduce fiber gradually. I’ve been reading a lot about psyllium husk, and some people suggest starting with 5g, mixing it with water, and drinking it immediately before it turns into a gel.
What’s been your experience with this? Any tips or recommendations?
r/Microbiome • u/Over-Parfait-3099 • 1d ago
Out of curiousity, has anyone taken Avelox? What were your side effects afterwards? I was prescribed a 10 day 400 mg course for a nasty secondary infection from a brown recluse bite, and while it got rid of the infection (yay) I just finished it four days ago and I am SO tired. Like can't think straight tired, heavy eyes kinda tired. I Googled it and it said recovering from the bite itself or the meds could do that, but how long does it last? I go back for my regular wellness check in 4 weeks. I hope its over by then.
r/Microbiome • u/UltachIontach • 2d ago
As the title suggests, my microbiome had taken a hit. I’m 24m.
basically anyone else dealt with a similar level of disruption and came out okay?
i‘m also struggling with ongoing malabsorption 2 months after the last antitbioc and 3 since the giardia.
i suspect deficiencies for several reasons.
I am worried, and as inappropriate as it might sound now, im worried about returning to an occasional binge drink (Irish here).
I’d appreciate any help and shared anecdotes!
Buíochas!
r/Microbiome • u/arnzr_nutrition • 2d ago
One issue that comes up with oral iron is the portion that is not absorbed. Free iron remaining in the lumen can influence the gut environment and has been shown in several studies to affect microbial composition.
This is part of the reason different iron forms are discussed in the context of gut tolerance. Ferrous sulfate tends to leave more residual iron and is more often linked with digestive complaints. Forms with higher bioavailability, such as iron bisglycinate, generally result in less unabsorbed iron. Liposomal iron is sometimes used for a similar reason — more of the iron is encapsulated during transit.
None of these completely eliminate contact with the gut, but the amount of free iron left behind does differ between forms.
Anyone here looked into the microbial effects of different iron preparations?
r/Microbiome • u/mlhnrca • 3d ago
r/Microbiome • u/stescarsini • 2d ago
Which microorganisms make an unbalance microbiome with a GI tract not being able to absorb nutrients and instead releasing them in the blood vessels?
thank you
r/Microbiome • u/the_practicerLALA • 2d ago
Hello, I have methane SIBO and gut dusbiosis, can you recommend my an Iron supplement that will bypass that please?